Search results for " set membership"
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Identification and validation of quasispecies models for biological systems
2009
An identification procedure for biological systems cast as quasi-species models is proposed. Their identification is a challenging problem because of the bilinear dependence on the parameters and their physical constraints. The proposed solution is within the framework of set-membership identification. %The bilinear dependence on parameters of the model and their physical constraints make the present issue challenging. We determine an estimate of the model parameters together with their interval of variability (Uncertainty Intervals), taking into account all the physical constraints. Invalidation/validation is performed on the basis of the predictive capability of the estimated models. The …
Application of model quality evaluation to systems biology
2008
Application of model quality evaluation to the quasispecies models is presented. These models are useful for the analysis of the DNA and RNA evolution and for the description of the population dynamics of viruses and bacteria. An estimate of the parameters together with their interval of variability is computed and the quality evaluation is tested on the basis of the model prediction error capability.